Men with family history of prostate cancer have a higher risk of disease recurrence after radical prostatectomy

M Thalgott, M Kron, JM Brath, DP Ankerst… - World journal of …, 2018 - Springer
… Self-reported FH of PC was verified by histopathological reports … to the “Union international
contre le cancer” version 2002 for … Notably, early onset PC (≤ 55 years) was observed more …

Family History and Prognosis of Prostate Cancer

F Jansson - 2020 - search.proquest.com
… • Two or more relatives with early onset prostate cancer, ie … G84E and association to
significant prostate cancer is … pathology after prostatectomy is not known. We aim to evaluate if …

[HTML][HTML] Prostate cancer in young adults—Seventeen-year clinical experience of a single center

TH Huang, JY Kuo, YH Huang, HJ Chung… - … Medical Association, 2017 - Elsevier
… %) had a family history of prostate cancer in our study group. … approximately 43% of early
onset disease (in those younger … similar histological grade, disease stage, PSA level, disease

[PDF][PDF] Molecular evolution of early-onset prostate cancer identifies molecular risk markers and clinical trajectories

C Gerhauser, F Favero, T Risch, R Simon, L Feuerbach… - Cancer cell, 2018 - cell.com
… We detected significant associations between germline PTVs in … We tested the ability to
predict the disease course based on a … Histopathological data were retrieved from the patient’s …

Germline Variants in DNA Damage Repair Genes and HOXB13 Among Black Patients With Early-Onset Prostate Cancer

MR Trendowski, C Sample, T Baird… - JCO Precision …, 2022 - ascopubs.org
early-onset prostate cancer and/or a positive family history of … Its association with age at
onset and advanced disease in … of relevant clinical data but also histopathologic confirmation of …

[HTML][HTML] Polygenic risk score for genetic evaluation of prostate cancer risk in Asian populations: A narrative review

SH Song, SS Byun - Investigative and clinical urology, 2021 - ncbi.nlm.nih.gov
… to early onset and aggressive disease [26,27], PCa, like most … (SNP) with positive or negative
associations are becoming … and aggressive PCa pathology compared to Caucasian and …

[HTML][HTML] Prostate cancer between prognosis and adequate/proper therapy

T Grozescu, F Popa - Journal of medicine and life, 2017 - ncbi.nlm.nih.gov
… 50-59 showed a histopathological proof of prostate cancer, and the … , having an autosomal
dominant trait and an early onset (… association than all the other with the aggressive forms of …

Is early-onset cancer an emerging global epidemic? Current evidence and future implications

T Ugai, N Sasamoto, HY Lee, M Ando… - … Reviews Clinical …, 2022 - nature.com
… Data from another study indicate a positive association between birthweight and colon cancer
risk in adulthood 30 . Exposure to ionizing radiation and age at menarche are other factors …

[HTML][HTML] Prostatic cancers: understanding their molecular pathology and the 2016 WHO classification

K Inamura - Oncotarget, 2018 - ncbi.nlm.nih.gov
… diseases with variable clinical courses. In accordance with … Health Organization (WHO)
classification of prostatic cancers … unique subset of early onset prostate cancers, with relatively …

Early-onset baldness and the risk of aggressive prostate cancer: findings from a case–control study

NP Papa, RJ MacInnis, DR English, D Bolton… - Cancer Causes & …, 2018 - Springer
… the association between aggressive PC and very early-onset … meeting the following four
criteria: (a) histological Gleason … adjusted for family history of PC, very early-onset baldness …